The first meeting of the Informal Dialogue on Drugs Policy in Latin America took place in Montevideo, Uruguay. The meeting had the support of the National Drugs Council in Uruguay (Junta Nacional de Drogas or JND). Twenty-five people took part from eight countries in Latin America, Europe and the US. Three sessions centred around: (1) Consumption of base paste and crack in the South of Latin America; scientific and political responses. (2) Overview of the UNGASS review and evaluation process for the period 2008/2009, and discussion of the contributions from the point of view and practices of Latin American countries. (3) The prison problem in the region associated with drug related crimes: realities, problems and proposals.